Focusbiomolecules 10-1363說明書
$ 70.00
Mitoquinone(444890-40-9)是一種靶向線粒體的抗氧化劑。顯示心臟和神經保護作用。1 在阿爾茨海默病的小鼠模型中顯示有益效果。2 Mitoquinone保護胰腺β細胞免受氧化應激并改善胰島素分泌。3 細胞可滲透。
CAS:
444890-41-9
目錄編號:
10-1363
活動:
線粒體靶向抗氧化劑
化學名稱:
10-(6'-泛醌基)癸基三苯基溴化鏻
分子量:
663.64
分子式:
C 37 H 44 BrO 4 P.
溶解性:
溶于DMSO。
物理特性:
棕色蠟狀固體
純度:
通過TLC
NMR測定98%(符合)
貯存溫度:
-20°
穩定性:
供應穩定3年。DMSO中的溶液可以在-20°下儲存長達3個月。
運輸代碼:
RT
參考文獻/引文
1)Ghosh 等。(2010),帕金森病模型中線粒體靶向藥物的神經保護作用 ; 自由基。生物學。Med。,49 1674
2)McManus 等。(2011),線粒體靶向抗氧化劑MitoQ防止阿爾茨海默病轉基因小鼠模型中空間記憶保留和早期神經病理學的喪失 ; J.Neurosci。,31 15703
3)Lim 等人。(2011),靶向線粒體的抗氧化劑保護胰腺β細胞免受氧化應激,改善胰島素分泌的葡萄糖毒性和糖脂毒性 ; 細胞生理學。Biochem。,28 873
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